Adhesion molecules and differentiation syndrome: phenotypic and functional analysis of the effect of ATRA, As2O3, phenylbutyrate, and G-CSF in acute promyelocytic leukemia
Background and Objectives Differentiation Syndrome (DS) is a treatment complication which can occur in patients treated with acute promyelocytic leukemia (APL) with napoleon concealer all transretinoic acid (ATRA) or As2O3, and is characterized by enhanced leukocyte transmigration.As2O3, Phenylbutyrate (PB) and G-CSF are known to potentiate ATRA ef